Level 1
Theoretical association
Biologically plausible support from preliminary research.
ProbiEase
Evidence-based Probiotic–Disease Database
Explore curated probiotic entities, structured experimental evidence, and probiotic–disease associations.
ProbioticEvidenceDisease
Key Features
Three direct ways to explore the ProbiEase database.
Probiotic Profiles
Browse strain- and species-level records with taxonomic and microbiological annotations.
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Experimental Evidence
Search structured probiotic–disease evidence with experimental details and literature sources.
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Knowledge Graph
Interactively explore probiotic–disease associations and supporting evidence.
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Database Overview
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Evidence Framework
Four evidence categories and a concise literature-to-database workflow.
Level 2
In vitro evidence
Effects observed in culture or cell-based systems.
Level 3
Animal model evidence
Associations evaluated in a preclinical whole-organism model.
Level 4
Human trial evidence
Associations supported by a human interventional study.
Evidence level reflects the type of supporting experimental evidence and should not be interpreted as a direct measure of treatment efficacy.
Database Construction Workflow
- 01LiteraturePubMed studies
- 02ScreeningEligibility criteria
- 03ExtractionStructured evidence
- 04StandardizationTaxonomy and disease
- 05ClassificationEvidence levels
- 06DatabaseValidated records
Evidence Snapshot
A focused view of leading disease associations and record completeness.
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